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Melatonin Receptors

Summary

Rozerem (ramelteon) is a prescription insomnia medication that was approved by the FDA in July 2005 and began to be marketed to consumers in 2006. Rozerem has a unique mechanism of action – melatonin receptor agonist -- that selectively targets specific receptors in the brain that are responsible for controlling the body’s sleep-wake cycle. It works by mimicking melatonin, a naturally occurring hormone that is produced during the sleep period.

Brand names

Rozerem

How it works

Acts like melatonin.

Price

Rozerem 8 mg. tablets     quantity 30      $104.93

Source: Drugstore.com

Side Effects & Risks

Can cause next day drowsiness.

Best used for

People who can't fall asleep; not for those who wake up during the night. Also useful for people dealing with circadian-rhythm issues caused by jet lag or shift work. 

Rozerem

Rozerem is a sedative, also called a hypnotic. It works by affecting certain substances in your body that help regulate your "sleep-wake cycle".

Rozerem is used to treat insomnia that is associated with having trouble falling asleep.

Unlike some other sleep medications, Rozerem is not known to be habit-forming.

Do not use this medication if you are allergic to ramelteon, or if you have severe liver disease. You should not take Rozerem if you are also taking the antidepressant fluvoxamine (Luvox).

Rozerem Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives, difficulty breathing; swelling of your face, lips, tongue or throat. Stop taking Rozerem and call your doctor of you have:

  • a missed menstrual period

  • nipple discharge

  • loss if interest in sex

Less serious side effects may include:

  • drowsiness

  • dizziness

  • headache

  • nausea

  • diarrhea

  • runny nose, stuffy nose, sore throat  

 

Source: SleepWeb (Marketdata Enterprises, Inc.) research, FDA

*page last updated  05/12/2008

 

 

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